Beckhaus, Steffi; Geiger, Christian; Pöpel, Cornelius; Reckter, Holger (2009)
Workshop-Proceedings der Tagung Mensch & Computer 2009. Grenzenlos frei!? Berlin, 06.-09.09.2009. Berlin: Logos Verlag, 153-154.
Kohls, Niko; Sauer, Sebastian; Walach, Harald (2009)
Personality and Individual Differences 46 (2), 224-230.
DOI: 10.1016/j.paid.2008.10.009
Durst, Carolin (2009)
ERP-Management - Zeitschrift für unternehmensweite Anwendungssysteme 3, 29.
Löffler, Carolin (2009)
Proceedings of the IADIS International Conference E-Commerce 2009. Algarve, Portugal, 19.-21.06.2009. Lisboa: IADIS Press, 210-214.
Durst, Carolin; Zagel, Christian; Körber, Philipp (2009)
Proceedings 2009 Verband der Hochschullehrer für Betriebswirtschaft. Nürnberg.
Müller, Jochem; Sauter, Ulrich (2009)
Lohmar: Josef Eul Verlag.
Müller, Jochem; Wildau, Nadine (2009)
Lohmar: Josef Eul Verlag.
Sover, Alexandru (2009)
Problemseminar an der Martin-Luther-Universität Halle-Wittenberg, Mai 2009.
Gaisser, Sibylle; Hopkins, Michael M; Liddell, Kathleen; Zika, Eleni; Ibarreta, Dolores (2009)
Gaisser, Sibylle; Hopkins, Michael M; Liddell, Kathleen; Zika, Eleni...
Nature 26 (7237), 458 | 407-408.
DOI: 10.1038/458407a
Gurwitz, David; Zika, Eleni; Hopkins, Michael M; Gaisser, Sibylle; Ibarreta, Dolores (2009)
Gurwitz, David; Zika, Eleni; Hopkins, Michael M; Gaisser, Sibylle...
Public Health Genomics 12 (3), 134-144.
DOI: 10.1159/000189625
This paper reviews the current situation in the field of pharmacogenetics/pharmacogenomics (PGx) in Europe. High expectations surrounding the clinical application of PGx remain largely unmet, as only a limited number of such applications have actually reached the market and clinical practice. Thus, the potential impact of PGx-based diagnostics on healthcare and its socio-economic implications are still unclear. With the aim of shedding some light on these uncertainties, the Institute for Prospective Technological Studies (IPTS) of the European Commission’s Joint Research Centre (JRC) has conducted a review of the ‘state of the art’ and a further analysis on the use of pharmacogenetics diagnostics for preventing toxic drug reactions and improving drug efficacy in Europe. The paper presents highlights from the JRC-IPTS studies and discusses possibilities for improving translation of PGx research in Europe by comparing some experiences in the USA. We also illustrate the related barriers for the clinical uptake of PGx in Europe with specific case-studies. Most of the barriers identified extend beyond the European context. This reflects the global problems of scarcity of data demonstrating proven clinical validity or utility and favorable cost-effectiveness studies to support the clinical application of PGx diagnostic tests in the clinical setting. Another key barrier is the lack of incentives for the private sector to invest in the development and licensing of PGx diagnostic tests for improving the safety and efficacy of out-of-patent drugs. It therefore seems that one key aspect where policy can affect the clinical uptake of PGx is via sustaining large-scale industry-academia collaborations for developing and proving the utility of PGx diagnostics.
Gaisser, Sibylle; Vignola-Gagné, Etienne; Hüsing, Bärbel; Enzing, Christien; van der Valk, Tessa (2009)
Gaisser, Sibylle; Vignola-Gagné, Etienne; Hüsing, Bärbel; Enzing, Christien...
6 (1).
DOI: 10.2217/17410541.6.1.93
Against the background of a number of first drug–diagnostic co-products developed and introduced into the European market, European decision-makers feel impelled to react and position themselves in the field of personalized medicine. Their reactions cover a broad range, from the analysis of knowledge requirements for market approval to the need for translational activities and the possible contribution of pharmacogenetics to public health. This article summarizes the current positions of European institutions, based on literature review and expert consultation for three items associated with personalized medicine: biobanks, genetic diagnostics and drug–diagnostic co-products, and provides an outlook on requirements for an effective future European policy on personalized medicine
Geißelsöder, Stefan (2008)
Sover, Alexandru; Frormann, Lars; Kipscholl, R. (2008)
26. Vortrags-und Diskussionsveranstaltung, Werkstoffprüfung 2008, Deutschen Verband für Materialforschung und –prüfung e.V., Dezember 2008.
Sover, Alexandru; Frormann, Lars (2008)
Abschlussbericht, Arbeitsgemeinschaft industrieller Forschungseinrichtungen „Otto von Guerick“ e.V. (AiF), (KF0188703VT6).
Sover, Alexandru; Frormann, Lars (2008)
13. Internationale Fachtagung Polymerwerkstoffe 2008, Halle/Saale, September 2008.
Sover, Alexandru (2008)
Steinbeis-Tag 2008, Stuttgart .
Pöpel, Cornelius (2008)
Workshop Proceedings der Tagungen Mensch & Computer 2008, DeLFI 2008 und Cognitive Design 2008. Lübeck, 07.-10.09.2008. Berlin: Logos Verlag, 116-119.
Geiger, Christian; Reckter, Holger; Paschke, David; Schulz, Florian; Pöpel, Cornelius (2008)
Geiger, Christian; Reckter, Holger; Paschke, David; Schulz, Florian...
Proceedings of the 2008 Conference on New Interfaces for Musical Expression (NIME08). Genova, Italy, 04.-08.06.2008, 303-306.
Knüpffer, Wolf (2008)
WISU - Das Wirtschaftsstudium 02/2008, 240-242.
Müller, Jochem; Le, Tan Thanh (2008)
Lohmar: Josef Eul Verlag (Controlling Forum - Wege zum Erfolg, Bd. 6).
Hochschule Ansbach
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